FKBP5 and post-traumatic stress disorder: Epigenetic regulation of FKBP5 and its association with patient’s behaviour is well documented: accelerated age-related decreases in FKBP5 methylation are associated with childhood trauma and depressive phenotypes (Zannas et al. 2016), while increased DNA methylation levels of FKBP5 have been found in patients suffering from post-traumatic stress disorders (PTSD) and major depressive syndromes (Kang et al. 2020).