PHACTR2 and hepatocellular carcinoma: LncRNAs are transcripts with more than 200 nucleotides, lacking protein-coding potential.3,4 Although thousands of lncRNAs have been identified, only a small number of them are well characterized in cancer progression.5,6 The lncRNA PHACTR2-AS1 (also known as NR027113 and LncIHS) was originally found to promote cell proliferation and invasion in hepatocellular carcinoma.7,8 However, PHACTR2-AS1(PAS1) plays the opposite role in breast cancer.