FBN1 rs201170905 additive model GG genotype (OR 1.900; 95% CI 1.308–2.761, P = 0.001), TGFB1 rs1800469 additive model AG genotype (OR 1.209; 95% CI 1.049–1.393, P = 0.013) or GG genotype (OR 1.193; 95% CI 1.009–1.411, P = 0.038) were found to be the risk factors for Stanford type B AD. This evidence concerns the gene TGFB1 and Alzheimer disease.