According to TCGA data, CTHRC1 expression was 6.222-fold higher in colorectal adenocarcinoma, 10.224-fold higher in mucinous colon adenocarcinoma, 4.803-fold higher in rectal adenocarcinoma, and 4.643-fold higher in cecum adenocarcinoma compared with normal tissues (Table 1). This evidence concerns the gene CTHRC1 and rectum adenocarcinoma.