UCN2 and infection: The SRP is a universally conserved complex that binds to the 80S ribosome and acts to co-translationally scan the nascent peptide to identify hydrophobic signal peptides present in integral membrane proteins and proteins secreted from the plasma membrane [84].NSP8 and NSP9 were observed that could bind to the 7SL RNA in the signal recognition particle and interfere with protein trafficking to the cell membrane upon infection [85].