MAD2L1 and neoplasm: Among them, the MAD2L1 gene can be used to predict patient prognosis (log-rank test P-value = 0.068, HR [95% CI] = 3.184[0.8562–11.84]), especially after many years of disease, the prognosis of patients with high expression of MAD2L1 (expression value greater than the median) is significantly worse, indicating that if the MAD2L1 gene can be down-regulated to prevent tumor cells from proliferating in large numbers, it may help the prognosis of patient (Fig. 8).