Then, active TB was taken as the dependent variable, and according to the results of univariate regression analysis, the clinical indexes such as expectoration, chest pain, low fever, hemoptysis, COPD, IFN-γ, IL-4, IL-6, IL-12, hypertension, and miR-378 with P < 0.1 were included as independent variables in the multivariate logistic regression analysis. This evidence concerns the gene IL4 and tuberculosis.