FH and leiomyoma cutis: Uterine leiomyomatosis is also associated with cutaneous leiomyomas and renal cell carcinoma in the hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome an autosomal dominant disorder with a mutation in the tumor suppressor gene coding for fumarate hydratase (fumarase).47 Two hundred families are known in the literature.47 Other organs may also develop tumors in this syndrome.26