In a previous study, platinum- and taxane-based neoadjuvant chemotherapy was associated with increased densities of CD3+, CD8+, CD8+ TIA-1+, PD-1+, and CD20+ TIL in ovarian cancer.52 In this study, we explored the dynamic changes of PD-L1 expression and TILs in tumors before and after neoadjuvant therapy. The gene discussed is CD8A; the disease is ovarian cancer.