The data showed that MDSCs in the spleens, mammary glands, and breast tumor tissues from Brca1-MT mice ﻿had similar inhibition to the proliferation of T cells and MDSCs from both spleen and tumor tissues in Brca1-MT mice had more suppressive effects on the proliferation of T cells than those from Brca1-WT mice (Fig. 1l–o). The gene discussed is BRCA1; the disease is neoplasm.