To investigate whether BRCA1 deficiency could induce defective immune response, we took advantage of our Brca1Co/Co;MMTV-Cre mouse model (GEMM)8 and performed immune profiling of wild-type (WT) mammary gland (WTMG), Brca1-mutant (MT) mammary gland (MTMG), tumor-adjacent mammary gland (Tu-adj. The gene discussed is BRCA1; the disease is neoplasm.