Besides, IHC and Western blot analysis revealed a positive correlation between CMTM6 and p21 expression in human HCC samples (r = 0.7351, P = 0.0002, Figs. 3K, L and S5E), whereas statistical analysis of the qPCR assays and datasets from TCGA database showed no significant correlation between CMTM6 and p21 mRNA expression. This evidence concerns the gene CMTM6 and hepatocellular carcinoma.