CDKN1A and hepatocellular carcinoma: Besides, IHC and Western blot analysis revealed a positive correlation between CMTM6 and p21 expression in human HCC samples (r = 0.7351, P = 0.0002, Figs. 3K, L and S5E), whereas statistical analysis of the qPCR assays and datasets from TCGA database showed no significant correlation between CMTM6 and p21 mRNA expression.