IDH1 and neoplasm: In addition, the IDH1+ tumor characteristics were associated with significantly higher RRT in [18F] FDopa and lower RRT in [18F]DPA-714 (respectively 2.70 [1.45; 3.23] min for IDH+ versus − 1.81 [− 3.04; − 0.75] min for IDH-, p = 0.03 and 11.07 [7.09; 15.69] min for IDH+ versus 22.33 [20.68; 23.76] min for IDH-, p < 0.01).