From the 140 common FUT8 glycoproteins, we further selected 19 membrane or receptor proteins with potential biological functions in cancer cell growth, proliferation, adhesion, or migration for further validation, including integrins (ITGA2, ITGA3, ITGA5, ITGA6, ITGAV, ITGB1, and ITGB5), cell-surface proteins (PTK7, TNFRSF21, JAG1, THBD, and CD44) and signaling receptors (AXL, CDCP1, NPR1, PTPRK, EGFR, OSMR, and IL6ST) (Additional file 5: Fig. S3, Figs. 5a, b and 8a). This evidence concerns the gene IL6ST and cancer.