Of note, the top 10 categories of molecular and cellular functions identified by these FUT8 targets from the two breast cancer cell lines seemed completely identical although in slightly different order (Additional file 2: Fig. S1a and b), which suggests that FUT8 indeed acts as a key regulator driving similar downstream pathologic processes of breast cancer (Additional file 2: Fig. S1c). This evidence concerns the gene FUT8 and breast carcinoma.