In agreement with these findings, we further confirmed 12 of these candidate FUT8 target proteins including IL6ST, OSMR, ITGA6, ITGAV, ITGB5, AXL, JAG1, NRP1, PTK7, PTPRK, CD44, or TNFRSF21 that are truly core fucosylated in breast carcinoma MDA-MB-231 cells (Fig. 4). The gene discussed is ITGB5; the disease is breast carcinoma.