SCARB2 and breast carcinoma: For instance, the Kaplan–Meier survival analysis revealed that breast cancer patients with high expression of ANO6 (Anoctamin 6, a multi-pass transmembrane protein that is a regulator of phospholipid scrambling) [20] or SCARB2 (Scavenger receptor class B member 2, a type III glycoprotein that is located primarily in limiting membranes of lysosomes/endosomes and participates in membrane transportation and the reorganization of endosomal/lysosomal compartment) [15] had a shortened survival compared to those in the low expression group (Fig. 3b, c).