Jakobsche et al. designed and synthesized an antibody-recruiting complex ARM-U1 by attaching chloromethyl ketone 2 and 2,4-dinitrophenyl (DNP) to the active site of uPA that mediated both antibody-dependent cellular phagocytosis (ADCP) and antibody-dependent cellular cytotoxicity (ADCC) against uPAR-expressing cancer cells [221]. This evidence concerns the gene PLAUR and cancer.