Notably, although mitochondrial glycerophosphate dehydrogenase (GPD2) has been implicated in the reoxidation of cytosolic NADH via the ETC in prostate cancer [70], due to compromised mitochondrial functions, this mechanism is unlikely to be at play in SCO2‐deficient HCT116 cells. The gene discussed is GPD2; the disease is prostate carcinoma.