This is consistent with the findings of previous studies that investigate the functions of circRNA in cancer, such as circ3823, which was found to be up-regulated in colorectal cancer, and it was shown to promote colorectal cancer growth, metastasis, and angiogenesis through the circ3823/miR-30c-5p/TCF7 axis [7]. This evidence concerns the gene TCF7 and colorectal cancer.