CD8A and glioma: DCs are the most important APCs in anti-glioma immunity priming.32 To determine whether MLVs activate CD8+ T cells by facilitating DC trafficking, we then quantified DC trafficking after RT by intratumoral injection of 0.5 μm FITC-labeled beads, which are too large to flow into MLVs and instead must be taken up by DCs in the tumor before being transported to the CLNs.