These results are consistent with our recent findings using a mouse glioma model with immunotherapy.20 In addition to DCs, whether MLVs could also play a role in enhancing RT-induced tumor-specific antigen release from irradiated cancer cells needs further investigation.47 Consistent with our recent findings,20 we demonstrated MLV expansion in mice with VEGF-C-overexpressing gliomas. Here, VEGFC is linked to central nervous system cancer.