For example, using IHC, Aiko et al. found that L-type amino acid transporter 4F2hc and LAT1 was increased in placental syncytiotrophoblast from pregnancies complicated by preeclampsia or intrauterine growth restriction (IUGR), suggesting an adaptive response to help maintaining growth in both of pregnancy complications26. This evidence concerns the gene SLC3A2 and preeclampsia.