Among the proteins which expression was increased by AF16 on human glioblastoma cells were proinflammatory chemoattractants of granulocytes, T cells and monocytes/macrophages (CCL3, CCL4, CCL7, CCL8, CCL20), T cell-stimulatory signals (CD40, TNFSF14, TNFrSF9), as well as metalloproteinases and other enzymes (MMP-1, MMP-10, uPA) or other molecules (IL8, TGFα). The gene discussed is MMP1; the disease is glioblastoma.