In addition, 4EGI-1, an inhibitor of eIF4E/eIF4G interaction [38], could also abrogate all these miR-495 knockdown-mediated effects on NPC cell proliferation, apoptosis, migration, and invasion (Fig. 6D–K and Supplementary Fig. 1E, F). The gene discussed is EIF4E; the disease is nasopharyngeal carcinoma.