CircTMTC1 (circRNA ID: hsa_circ_0025767, chr12: 29,904,598–29,911,710), originating from exons 3, 4 and 5 of the TMTC1 gene on the chromosome 12 (Fig. 1A), has been identified one of the top 20 circRNAs which are differentially expressed in NPC [12]. Here, TMTC1 is linked to nasopharyngeal carcinoma.