CLDN7 and non-small cell lung carcinoma: In this study, we found that β-catenin activation upregulated the expression levels of claudin1, p-AKT, and pluripotency markers in EGFR mutant NSCLC cells, while 1,25D treatment suppressed expression levels of β-catenin, claudin1, p-AKT, and pluripotency markers.