We constructed two AML cell lines expressing MEF2D and IRF8, respectively, fused to the FKBP12F36V (dTAG) domain by a homozygous knock-in of the FKBP12F36V-coding DNA sequence into the endogenous TF-coding loci (Figs. 5A–C, 7A–C, below). This evidence concerns the gene IRF8 and acute myeloid leukemia.