In contrast, for metastatic BRAF-mutant melanoma, ALDH1A3 expression was correlated with the better OS [67]. Interestingly, in the present study, the Cox regression analysis revealed that ALDH1A3 was related to a better prognosis of UM patients (Hazard ratio = 0.735, P < 0.05). The gene discussed is ALDH1A3; the disease is melanoma.