The data revealed that treatment with CM of activated RAW264.7 enhanced Sca-1 expression (13.5%) and ALDH1 activity (14.9%) in cancer cells as compared to their respective controls (7.2 and 5.5% respectively) and this effect was inhibited on pre-treatment with Stattic (6.1 and 8.4% respectively) (Fig. 4D, E). This evidence concerns the gene ALDH1A1 and cancer.