Furthermore, among such 15 synonymous mutation of SDHB gene, 9 tumor had RET gene mutation: exon 11, c.1901G > T, p.Cys634Phe (rs75996173): exon 11, c.2071G > A, p.Gly691Ser (rs1799939): or exon 11, c.1925 T > C, p.Val642Ala (rs766962871). Here, RET is linked to neoplasm.