The tumor cells of SDHB-, SDHC-, and SDHD-mutated tumors were reported to show absence of SDHB immunostaining, whereas those of non-SDH mutated tumors showed strong SDHB immunostaining, and SDHB immunohistochemistry was found to have 100% sensitivity and 84% specificity in detecting mutations [34]. Here, SDHB is linked to neoplasm.