Furthermore, we identified robust evidence of a causal association with HF as indicated by sign concordance of all MR point estimates from the multiverse sensitivity analysis for 8 proteins: ADM (adrenomedullin), CHI3L1 (chitinase-3-like protein 1), CSF-1 (macrophage colony-stimulating factor 1), CTSL1 (cathepsin L1), FGF-23 (fibroblast growth factor 23), Gal-3 (galectin-3), MMP-12 (matrix metalloproteinase-12), and KIM-1 (kidney injury molecule 1). The gene discussed is LGALS3; the disease is hydrops fetalis.