BRCA1 and breast cancer: According to the consensus of experts and guidelines, the criteria for candidates to do BRCA1 genetic testing are (Daly et al., 2021): 1) BC patients before the age of 40 years; 2) BC patients before the age of 50 years old who had a second primary BC or a history of BC or pancreatic or prostate cancer in their relatives; 3) patients with TNBC before the age of 60 years old; 4) all male BC patients; 5) patients with bilateral BC; and 6) Patients with a relevant family history at any age, who want to be assessed for cancer risk.