Integrin α11β1 has been shown to promote tumor growth and metastatic potential of non-small cell lung cancer (NSCLC) cells (Navab et al., 2016), breast cancer, in conjunction with platelet-derived growth factor receptor β (PDGFRβ) (Primac et al., 2019), and in head and neck squamous cell carcinoma (HNSCC) and pancreatic ductal adenocarcinoma (PDAC) (Zeltz et al., 2019). This evidence concerns the gene PDGFRB and head and neck squamous cell carcinoma.