NFKB1 and glioblastoma: More recently, one study has exposure U251 GBM cell line to different concentrations of GA (1, 2, and 4 mM), and the authors have observed inhibition on cell proliferation and colony formation, apoptosis stimulation, and significantly decreasing in p65 protein, responsible for nuclear factor kappa B (NF-κB) pathway activating (24).