In a panel of 11 glioma cell lines, IngC acted as a potent inhibitor of protein kinase C (PKC) activity by PDK1 inhibiting and consequently tumor invasion and migration impairment through Wnt/β-catenin (β-C) pathways by lower concentration the effector protein β-C (93) (Figure 2B). Here, PRRT2 is linked to glioma.