Except for sarcoma cancer, compared with normal tissues, the expression level of FAT10 gene in all other available cancer tissues was significantly up-regulated, including brain and central nervous system cancer, breast, cervical, colorectal, esophageal, gastric, head and neck, liver, lung, lymphoma, ovarian, kidney, and pancreatic tissues (Figure 1A). The gene discussed is UBD; the disease is central nervous system cancer.