CTHRC1 and neoplasm: Through the enrichment analyses of GO and KEGG, the mechanism of CTHRC1 in biological processes, not only its cellular components and molecular function were defined, but also the specific regulatory pathways (such as AGE-RAGE, Relaxin and Pl3K signalling pathways) and action targets (including protein digestion and absorption, ECM-receptor interaction, focal adhesion and platelet activation) were identified, most of which are classical regulatory models that promote tumorigenesis or are involved in tumour development (Feng et al., 2009; Bao et al., 2019; Waghela et al., 2021).