Further subgroup analysis, based on the history of DM, found that fasting insulin (r = 0.169, P = 0.012), fasting C-peptide (r = 0.133, P = 0.049) and HOMA-IR (r = 0.162, P = 0.017) were all significantly positive related with T staging in patients without DM history. Here, INS is linked to diabetes mellitus.