However, DNAJC6 (PARK 19), DNAJC13 (PARK 21), SYNJ1 (PARK 20), VPS13C (PARK 23), and CHCHD2 (PARK 22) are also considered pathogenic and viewed as rare genetic contributors to PD disease (Olgiati et al., 2016; Puschmann, 2017; Schormair et al., 2018; Correia Guedes et al., 2020; Day and Mullin., 2021; Li B et al., 2021). This evidence concerns the gene SYNJ1 and Parkinson disease.