LRRK2 and Alzheimer disease: PD genes identified using this approach have demonstrated autosomal dominant (AD-PD) (SNCA, LRRK2), autosomal recessive (AR-PD) (PRKN, PINK1, DJ1) and X-linked (RAB39B) inheritance patterns (Bras and Singleton., 2011; Gasser, 2013; Bandres-Ciga et al., 2020).