There has been increased recognition that miR-139-3p could suppress the invasion and migration properties of breast cancer cells by targeting RAB1A (48), inhibit metastasis of cervical cancer by targeting NOB1 (49), restrain the proliferation, invasion, and migration of human glioma cells by targeting MDA-9/syntenin (50), and be used as a prognostic marker for a variety of tumors (51). Here, NOB1 is linked to central nervous system cancer.