NLRP3 and gastric cancer: Conversely, in a second independent intestinal-type GC patient cohort, the “Gastric Cancer Project ‘08 - Singapore Patient Cohort” (GSE15459) (33), comprising gastric tumor tissues (n = 177) and non-tumor gastric tissues (n = 92), NLRP3 mRNA levels were significantly upregulated in total gastric tumor tissues (Figure 1C).