At 1, 3, and 6 months of age, gastric Nlrp3 mRNA levels were significantly elevated (6- to 8-fold) in gp130F/F tumor-free gastric antrum (1 month old) or gp130F/F gastric antral tumors (3 and 6 months old) compared to either adjacent non-tumor antral tissue, or normal antral tissues of wild-type (WT) mice (Figure 2A). The gene discussed is NLRP3; the disease is neoplasm.