Furthermore, phosphorylation levels of NF-κB, which is activated downstream of inflammasomes to promote gastric tumorigenesis in the gp130F/F model (29), were also similar between gp130F/F and gp130F/F:Nlrp3-/- gastric tumor or non-tumor samples (Figures 4A, D). The gene discussed is NLRP3; the disease is gastric neoplasm.