We also note that the expression of several angiogenesis-related genes (Cxcl1, Cxcl2, Mmp2, Mmp9, and Vegf) was comparable among gastric tumor and non-tumor tissues from 3mo and 6mo gp130F/F and gp130F/F:Nlrp3-/- mice (Figure 6G and Supplementary Figure 3E). Here, CXCL2 is linked to gastric neoplasm.