Several studies have shown that stress not only simulates NF-κB activation and monocyte migration to the intestine (Jang et al., 2018) but also improves the density of Aspergillus and E. coli in the gut microbiota and increases fecal and serum LPS levels in rodents with anxiety-like behavior (Frankiensztajn et al., 2020). The gene discussed is NFKB1; the disease is Anxiety.