For validation of the mTORC1 axis, we examined the 4E‐BP1 and S6K phosphorylation, which represented the mTORC1 activity [35], in three HCC cells (PLC5, Huh7, and SK‐HEP‐1) under the treatment of SCT‐1015 (Fig. S8A). The gene discussed is EIF4EBP1; the disease is hepatocellular carcinoma.