Pre-treating BPH stromal cells with DHT induced the anti-inflammatory cytokine IL-10 and suppressed LOX-1 expression [4], thus blunting the ability of metabolic factors to trigger the secretion of proinflammatory cytokines (i.e. IL-8 and IL-6), as hereby observed in the prostate from TTh subjects. The gene discussed is CXCL8; the disease is benign prostatic hyperplasia.