TRAPPC9 and microcephaly: Of the TRAPP II complex specific subunits, only TRAPPC9 has been robustly associated with human disease, an autosomal recessive neurodevelopmental disorder (OMIM #613192) characterized by postnatal-onset microcephaly with reduced white matter volume and corpus callosum thinning, intellectual disability, dysmorphic features, hypotonia, epilepsy, and raised body mass index [18–20].