In retinal organoids total fraction, we detected upregulation of HGSNAT, a lysosomal acetyltransferase whose variants are the cause of RP‐73, and HKDC1, a hexokinase localized to the photoreceptor inner segment and associated with autosomal recessive RP, as well as Retinol dehydrogenase 11 (RDH11) associated with syndromic RP, and the MYO7A protein (Figure 4F) involved in Usher syndrome with an RP phenotype. Here, HGSNAT is linked to retinitis pigmentosa 1.