GSEA revealed that Notch signaling pathway was significantly enriched in the high‐risk group (Figure 3A–C); In terms of cancer hallmark, apoptosis, IL2‐STA5 signaling, and IL6‐JAK‐STAT3 signaling were the most relevant cancer hallmark in the low‐risk group, while hedgehog signaling pathway was dramatically enriched in the high‐risk group (Figure 3D–F). The gene discussed is IL6; the disease is cancer.