Subsequently, we investigated the relevance of these gene expressions with MM prognosis using bulk RNA‐seq data from the MMRF CoMMpass study and found that increased levels of these gene expressions, such as STMN1, TUBA1B, TUBB, TYMS and HMGN2 ranked the top five genes, were significantly associated with relapse risk and dismal OS (Figure 4C, Figure S19 and Table S7). Here, STMN1 is linked to Miyoshi myopathy.