To further confirm that these three interactors bind to SREK1 pre-mRNA, RIP analysis was performed, which showed that all the antibody targeting three interactors could recover SREK1L pre-mRNA (Fig. 7h), indicating that SRSF10 can interact with ELAVL1, PABPC and/or MAGOH/MAGOHB to regulate SREK1 splicing in HCC cells. Here, SREK1 is linked to hepatocellular carcinoma.