The suppression of anti-apoptotic Bcl-2 family members likely underlies the superior ability of CG-806 to abrogate survival of MCL cells in the lymph node-mimicking conditions, i.e., on BAFF and CD40L-expresing stroma, where induction of Bcl-xL and Mcl-1 is known to rescue neoplastic B cells from spontaneous and drug-induced apoptosis [18, 23]. Here, TNFSF13B is linked to mantle cell lymphoma.