METTL3 plays a dual role as either an oncogene or a tumor suppressor gene in various types of cancers, including hepatocellular carcinoma (HCC) [60, 61], hepatoblastoma [62], gastric cancer (GC) [63], colorectal cancer (CRC) [64], non-small cell lung cancer (NSCLC) [65, 66], and bladder cancer (BLC) [67, 68]. The gene discussed is METTL3; the disease is hepatocellular carcinoma.