CD4 and head and neck squamous cell carcinoma: In head and neck squamous cell carcinoma (HNSCC), METTL3 and HNRNPC were highly expressed in tumor tissue than normal tissue, high expression of METTL3 and HNRNPC were positively associated with the infiltration of CD4 naive T cells, CD4 memory-activated T cells, and eosinophils [74].