The results showed that the MFC LSD1 KO group exhibited equivalent tumor weight and volume than the MFC group in BALB/c nude mice, whereas tumors in the 615 mice were almost completely eradicated in the MFC LSD KO group (Fig. 1c and d), while their body weight stayed consistent (Supplementary Fig. 1e and 1f). This evidence concerns the gene KDM1A and neoplasm.