The levels of IFN-γ considerably (p < 0.05) increased in the animals treated with either probiotics or prebiotics (52.90 ± 7.16 and 51.74 ± 6.70 pg/ml, respectively) compared to the non-treated asthma group (22.85 ± 5.90 pg/ml), demonstrating that both the prophylactic treatments had the ability to modulate immune reactions by balancing Th1/Th2 responses in lungs (Fig. 1). Here, IFNG is linked to asthma.