ERBB2 and neoplasm: Although the exploratory analysis of the combined TCGA-BRCA and METABRIC dataset showing superior RFS in “ERBB2 neutral” tumours provides additional insight on the differences in outcome among HER2-negative BCs, the number of BCs with both IHC and CNV data in TCGA-BRCA series was limited, especially for HER2-zero and IHC 2+ ISH− tumours.