In the group of 44 patients with positive autoAbs against the 5 PDC subunits, 8 (18%) had elevated GGT, 5 (11%) had elevated ALT, and 7 (16%) had elevated AST, while 2 (5%) had increased total bilirubin, and only one patient had increased ALP (Table 1) but not enough criteria to fulfill a diagnosis of PBC except for 4 SSc cases who had a defined PBC diagnosis and were in hepatologic follow-up and treatment. The gene discussed is GPT; the disease is systemic sclerosis.