Based on our analysis, we identified an 11 PRG gene signature, namely, AIM2, CASP1, ELANE, GSDMB, GSDMC, IL1B, NLRP1, GZMB, IL1A, CHMP7, and CYCS, that is related to MM patient prognosis. The gene discussed is CYCS; the disease is Miyoshi myopathy.